Calpol 650 Tablet 1*15

Description

Manufacturer:
Glaxo SmithKline Pharmaceuticals Ltd

Salt Composition:
Paracetamol (650mg)

Description:

Calpol 650 Tablet contains paracetamol, also known as acetaminophen, a widely used analgesic (pain reliever) and antipyretic (fever reducer). It is a non-opioid medication that works through mechanisms primarily within the central nervous system. While the exact pathways are not fully elucidated, it is believed that paracetamol inhibits the synthesis of prostaglandins, chemical messengers that play a key role in the body’s inflammatory response and the transmission of pain signals. Specifically, it is thought to inhibit cyclooxygenase (COX) enzymes, particularly COX-2, in the brain and spinal cord. However, its anti-inflammatory effects in peripheral tissues are minimal, which distinguishes it from non-steroidal anti-inflammatory drugs (NSAIDs).

As an analgesic, paracetamol is effective in relieving mild to moderate pain such as headaches, muscle aches, toothaches, menstrual cramps, and pain associated with colds and flu. It acts by raising the pain threshold, meaning a greater stimulus is required to elicit a pain sensation. Unlike opioids, paracetamol does not produce euphoria or respiratory depression and is not associated with physical dependence.

As an antipyretic, paracetamol reduces fever by acting on the hypothalamus, the part of the brain that regulates body temperature. It is thought to inhibit the production of pyrogens, substances that cause fever, and to increase heat loss from the body through vasodilation and sweating. This makes it a common choice for managing fever associated with infections or vaccinations.

Calpol 650 Tablet contains a higher dose of paracetamol (650 milligrams) compared to standard paracetamol tablets (often 500 mg). This higher strength may be preferred for adults experiencing more intense pain or higher fevers, providing a more potent effect with a single dose. However, it is crucial to adhere to the recommended dosage and not exceed the maximum daily limit of paracetamol, as exceeding this can lead to serious liver damage. The maximum recommended daily dose for adults is typically around 4000 mg, but lower limits are often advised to minimize risk.

od thinners