Description
Manufacturer:
Zydus Lifesciences Ltd
Salt Composition:
Teneligliptin, Metformin hydrochloride
Description:
Tenglyn M 500mg Tab is a combination oral antidiabetic medication containing teneligliptin and metformin hydrochloride. It is used in the management of type 2 diabetes mellitus to improve glycemic control through the complementary actions of its two active ingredients.
Teneligliptin, as detailed in the description for Tenglyn 20mg Tab, is a DPP-4 inhibitor that enhances the effects of incretin hormones, leading to increased insulin release and decreased glucagon secretion in a glucose-dependent manner. This helps to lower blood glucose levels, particularly after meals, with a low risk of hypoglycemia when used alone.
Metformin hydrochloride is a biguanide that works primarily by reducing the production of glucose by the liver (hepatic gluconeogenesis), increasing the sensitivity of peripheral tissues to insulin (improving glucose uptake and utilization), and decreasing the absorption of glucose from the gastrointestinal tract. Metformin is a cornerstone in the treatment of type 2 diabetes and is known for its effectiveness in lowering blood glucose levels and its potential cardiovascular benefits. The 500mg strength in Tenglyn M may be formulated as either immediate-release or sustained-release, which can affect the dosing frequency and tolerability. Sustained-release formulations are often associated with fewer gastrointestinal side effects and allow for once-daily dosing.
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