Description
Manufacturer:
Abbott India Limited
Salt Composition:
Sofosbuvir
Description:
Vonefi 10mg Tab contains sofosbuvir, an antiviral medication primarily used in the treatment of chronic hepatitis C virus (HCV) infection. Sofosbuvir is a nucleotide analog inhibitor of the HCV NS5B RNA-dependent RNA polymerase, an enzyme essential for the replication of the hepatitis C virus.
By inhibiting this enzyme, sofosbuvir effectively blocks the virus from multiplying in the body, leading to a reduction in viral load and ultimately a virologic cure in many patients. Vonefi is typically used in combination with other antiviral medications, such as ledipasvir, velpatasvir, or ribavirin, depending on the specific genotype of HCV, the presence of cirrhosis, and prior treatment history.
The standard dosage of sofosbuvir is 400 mg once daily, but Vonefi is available in a 10 mg strength, suggesting it may be used for pediatric patients or those requiring lower doses, although the specific indication for this lower strength would be determined by the prescribing physician. Treatment duration usually ranges from 8 to 24 weeks, depending on the specific HCV genotype and the other medications used in combination.
Sofosbuvir-based regimens have revolutionized HCV treatment due to their high efficacy, shorter duration, and fewer side effects compared to older interferon-based therapies. Common side effects of sofosbuvir are generally mild and may include fatigue, headache, nausea, and insomnia.
However, the side effect profile can vary depending on the other medications used in combination. It is crucial for patients undergoing HCV treatment with Vonefi to be closely monitored by a hepatologist or infectious disease specialist. Regular blood tests are necessary to track viral load and assess liver function. Vonefi is a prescription medication and should only be used under the guidance of a qualified healthcare professional experienced in the management of hepatitis C.
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